EasySeq NGS Targeted Capture Kit for BRCA1 and BRCA2
The EasySeq NGS Targeted Capture Kits provide a complete workflow for routine Next Generation DNA sequencing. Using sequence capturing with single molecule Molecular Inversion Probes (smMIP)1, followed by a barcoding Amplification step, the system enables sequencing of the BRCA1 and BRCA2 genes in a simple, fast and robust workflow, resulting in 100% coverage of the coding regions of both genes with double probe tiling by two independent probes.
For data analysis, NimaGen is partnerring with JSI Medical Systems to provide a powerful all-in-one solution for robust high-throughput variant detection and interpretation the NGS data.
NGS Sequencing kits
The kits contain reagents for capturing the complete coding regions and subsequently tag the specific sample sequences with unique barcoding, enabling sequencing of up to 384 DNA samples in one sequence run. The resulting libraries are compatible with all Illumina sequencing platforms.
All smMIP probes are manufactured by Biolegio, a global leader in long oligos. (www.biolegio.com)
1 Hiatt et al., Genome Res. 2013 May: 23(5):843-854
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