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The kit consists of two recombinant hydrolytic enzymes: Exonuclease-I and Shrimp Alkaline Phosphatase. Together they eliminate all unwanted dNTP’s and residual primers from your PCR products, which would interfere with downstream applications.
With ExS-Pure™ there is no need for time-consuming gel, column or magnetic bead purifications. Both short and long stranded PCR products are left completely intact.
DNA sequencing, SNP analysis and many other applications require PCR products which are free of dNTP's and primers. For DNA sequencing, unincorporated primers and dNTP's can lead to high background and miscalling of bases. With Ex's-Pure you can efficiently remove these contaminants and make improvements in read length and base calling.
The straightforward workflow allows the cleanup to be performed in under 10 minutes, including hands-on time.
I've just received the sequencing results and I'm quite impressed by the quality of the traces.