AmpliClean™ drop-in alternative to AMPure® XP: Same for less

GOLD-STANDARD EQUIVALENT PERFORMANCE AT A COMPETITIVE PRICE

AmpliClean™: Fast and reliable DNA cleanup without the complexity

You know the trade-off

The industry-standard magnetic beads deliver consistent results. But they come at a premium price that strains your budget. Cheaper alternatives promise savings, but batch-to-batch variation keeps you guessing whether today's cleanup will match yesterday's. You shouldn't have to choose between quality or cost.

AmpliClean™: consistent results, competitive pricing

NimaGen's AmpliClean™ combines proven magnetic bead technology with cost-effective pricing. Designed as a trusted drop-in alternative to AMPure® XP, AmpliClean™ recovers DNA fragments >100 bp with the consistency and reproducibility your workflows demand without the premium price tag.

AmpliClean™ cleanup kit

  • Designed for standard cleanup of DNA fragments >100 bp
  • High-yield, high-purity DNA for PCR purification, Sanger Sequencing, and NGS
  • Cost-effective alternative to AMPure® XP beads
THREE-STEP PROCESS

The simple workflow you know, now optimized

AmpliClean™ follows the same trusted three-step process you rely on:

  • Bind – Long DNA fragments selectively bind to paramagnetic beads
  • Wash – Salts, primers, dimers, nucleotides, and short contaminants are removed with ethanol
  • Elute – Ultra-pure DNA is recovered, directly ready for downstream applications

No centrifugation. No vacuum filtration. Just reliable, high-quality DNA in three simple steps.

“NimaGen’s AmpliClean™ combines proven magnetic bead technology with cost-effective pricing.”

Why labs trust AmpliClean™?

Consistent, reproducible results

Every cleanup delivers the same high recovery and purity. No batch variation, no protocol adjustments, no surprises. Your results stay consistent from the first reaction to the thousandth.

Complete contaminant removal

Primers, primer-dimers, salts, dNTPs; AmpliClean™ removes them efficiently and completely. The result: ultra-pure DNA ready for immediate downstream use.

Cost-effective performance

Delivers gold-standard equivalent results at a competitive price point. An economical choice for both routine purification and high-throughput sequencing applications.

Tired of unwanted short fragments?

For DNA fragments between 1-6 kb, explore AmpliClean™ LF, specifically optimized for long-fragment cleanup with superior removal of short contaminants

AMPLICLEAN WORKS

Why choose AmpliClean™?

  • Reliable results: high recovery and purity, every time
  • Superior performance for long fragments: proven removal of short background DNA
  • Validated by customers: improved sequencing specificity and data quality
  • Automation-ready: compatible with Alpaqua® magnet plates and liquid handlers
  • Flexibility: suited for both small-scale manual workflows and high-throughput automation
AUTOMATION-READY FOR ANY LAB

AmpliClean™ adapts to your setup

Whether you run manual single-tube workflows or high-throughput sequencing facilities, AmpliClean™ adapts to your setup. The protocol offers high flexibility for manual operation and integrates seamlessly with liquid handling systems. Fully compatible with Alpaqua® magnet plates (96-well and 384-well formats), making it ideal for labs scaling up their sequencing operations.

 

Ideal applications

  • PCR product purification
  • Sanger sequencing cleanup
  • NGS library preparation
  • Microarray sample preparation
  • Any workflow requiring reliable removal of primers, salts and nucleotides

Request your AmpliClean™ test sample 

Want to see consistent results in your own workflow? Request a test sample of AmpliClean™ and experience reliable magnetic bead cleanup at a competitive price.


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