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Product Information

Magnetic Bead-based Amplicon Cleanup

Intended use

AmpliClean™ provides highly efficient and cost-effective magnetic bead-based technology for high-throughput purification of PCR products. It requires no centrifugation or vacuum filtration steps. Purified products can be used directly for downstream applications such as Sanger sequencing, NGS or microarrays. With its high flexibility it can be applied for standard cleanup and size selection. 

 

AmpliClean™ magnetic beads are recommended for use in DNA sequencing workflows, from input DNA to sequencing-ready NGS libraries. AmpliClean™ removes, salts, primers, primer-dimers and dNTPs, leaving ultra-pure DNA of the desired length. Purified products can be used directly for downstream applications such as Sanger sequencing, NGS and microarrays. 

 

AmpliClean™ magnetic beads are the widely adopted alternative to AMPure XP beads for purification and cleanup.

Compatibility

The AmpliClean™ protocol is highly flexible for manual operation and can be easily incorporated in any liquid handling system. For both applications, NimaGen offers Alpaqua magnet plates, the leading brand for magnetic separation devices. The plates are used in combination with AmpliClean™ or other magnetic bead-based products.

 

Alpaqua magnet plates are optimized for automation platforms, using integrated Spring Cushion Technology, enabling maximized sample aspiration and protecting instruments and consumables.

 

AMPure XP is a trademark of Beckman Coulter.

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Alpaqua® Magnet Plates

NimaGen offers a broad range of Alpaqua® magnet plates, the leading and most frequently recommended brand for magnetic separation devices.

Alpaqua® magnets are the most widely used magnet plates used in combination with AmpliClean™ Cleanup Kit or AMPure XP for cleanup of PCR reactions or preparation of sequencing ready NGS libraries.

View Alpaqua® Magnet Plates